Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189176 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL27341644 | 0.78 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1CYP3A4ADH1CADH1A | |
| SCHEMBL2668555 | 0.74 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1CYP3A4ADH1CADH1A | |
| SCHEMBL28267341 | 0.74 | — | — | |
| SCHEMBL6074931 | 0.74 | SIGMAR1 (0.41) | ALDH1A1CYP3A4LMNA | |
| Hydrochloric Acid SCHEMBL27363306 | 0.73 | ADH1C (0.44) | L3MBTL1ALDH1A1ADH1CADH1AADH4 | |
| SCHEMBL28866726 | 0.73 | ADH1A (0.38) | L3MBTL1ALDH1A1ALDH2CYP3A4ADH1C | |
| SCHEMBL8602631 | 0.72 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1ADH1CADH1AADH4 | |
| SCHEMBL503798 | 0.72 | MEN1 (0.35) | L3MBTL1CYP3A4ADH1CADH1AADH4 | |
| SCHEMBL2371705 | 0.72 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1CYP3A4ADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446699-B1 | Inhibitors of nitric oxide biosynthesis | MERRELL PHARMA INC (US) | 2000-05-31 | — | — | EP | disclosed |
| US-5710324-A | AMINE CONTAINING COMPOUNDS | MERRELL PHARMACEUTICALS INC. (US) | 1998-01-20 | — | — | US | disclosed |
| US-5318992-A | Administering for the treatment of hypotensive conditions and shock | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0446699-A1 | Inhibitors of nitric oxide biosynthesis | MERRELL PHARMACEUTICALS INC. (US) | 1991-09-18 | — | — | EP | disclosed |