Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 4/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034054 | 0.87 | F2 (0.44) | MAPK8MAPK9MAPK10USP7RAB9A | |
| SCHEMBL8044126 | 0.86 | HDAC6 (0.36) | MAPK8MAPK9MAPK10USP7APEX1 | |
| SCHEMBL8042939 | 0.83 | RXRA (0.41) | MAPK8MAPK9MAPK10USP7GSK3B | |
| SCHEMBL8042807 | 0.82 | MEN1 (0.44) | MAPTRAB9A | |
| SCHEMBL8043915 | 0.79 | MAPK8 (0.37) | MAPK8MAPK9MAPK10USP7MAPT | |
| SCHEMBL8043583 | 0.79 | AKT1 (0.33) | MAPK8MAPK9MAPK10GSK3B | |
| SCHEMBL8050472 | 0.79 | MAPK8 (0.60) | MAPK8MAPK9MAPK10GSK3BMAPT | |
| SCHEMBL8043004 | 0.77 | MAPK8 (0.39) | MAPK8MAPK9MAPK10MAPTRAB9A | |
| SCHEMBL8034366 | 0.76 | ALDH1A1 (0.45) | MAPTRAB9A | |
| SCHEMBL8051741 | 0.75 | GSK3B (0.39) | GSK3BAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |