Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14557099 | 0.89 | KDM4E (0.43) | SMN1; SMN2CSNK2A2CSNK2A1RAB9ANPC1 | |
| SCHEMBL8047389 | 0.79 | CA1 (0.49) | SMN1; SMN2RAB9ANPC1KDM4EHDAC1 | |
| SCHEMBL8050989 | 0.79 | ALDH1A1 (0.60) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL9360268 | 0.79 | GAA (0.60) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL972899 | 0.79 | MGAM (0.60) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL8050331 | 0.79 | KIF11 (0.44) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL969040 | 0.78 | ALDH1A1 (0.52) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL8047555 | 0.77 | KDM4E (0.65) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL3826842 | 0.77 | HDAC1 (0.44) | SMN1; SMN2KMT2AMEN1CSNK2A2CSNK2A1 | |
| SCHEMBL969939 | 0.77 | KDM4E (0.59) | SMN1; SMN2KMT2AMEN1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112244031-A | Application of thiothiadiazole-containing nitrothiazole compound in prevention and treatment of agricultural plant diseases | 兰州大学 | 2021-01-22 | — | — | CN | disclosed |
| CN-104292224-B | Containing replacing 1,3,4-thiophene () diazole thioether benzothiazole amide derivatives and its preparation method and application | 贵州大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-104292224-A | Benzothiazole amide derivatives containing substituted 1,3,4-thiadiazole (oxadiazole) thioether as well as preparation method and application of derivatives | UNIV GUIZHOU | 2015-01-21 | — | — | CN | disclosed |
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |