Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | TOP2A | P11388 | 3/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3267344 | 0.82 | NCF1 (0.43) | HSD17B10ALDH1A1KDM4EMAPK9MAPK10 | |
| SCHEMBL963358 | 0.76 | ALOX5 (0.39) | RAB9AHSD17B10ALDH1A1KDM4ENPC1 | |
| SCHEMBL11626865 | 0.76 | L3MBTL1 (0.57) | RAB9AALDH1A1NPC1EGFRTOP2A | |
| SCHEMBL7995244 | 0.76 | ALDH1A1 (0.51) | RAB9AHSD17B10ALDH1A1KDM4ENPC1 | |
| SCHEMBL9866058 | 0.75 | AHR (0.51) | RAB9AHSD17B10ALDH1A1KDM4ENPC1 | |
| SCHEMBL26512422 | 0.73 | NCF1 (0.42) | RAB9AHSD17B10ALDH1A1KDM4ENPC1 | |
| SCHEMBL8035416 | 0.72 | L3MBTL1 (0.45) | RAB9AHSD17B10ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL959406 | 0.72 | TSHR (0.41) | RAB9AALDH1A1NPC1SMN1; SMN2MAPT | |
| SCHEMBL6262643 | 0.72 | MAPK10 (0.66) | HSD17B10ALDH1A1MAPK9MAPK10SMN1; SMN2 | |
| SCHEMBL10578784 | 0.71 | L3MBTL1 (0.44) | RAB9AHSD17B10ALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |