Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | PPIA | P62937 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028305 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL8040249 | 0.94 | PYGL (0.47) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL8037831 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL8040256 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL8037216 | 0.79 | SGMS2 (0.58) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL8035583 | 0.79 | SGMS2 (0.58) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL8039179 | 0.79 | PYGL (0.46) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL6162977 | 0.78 | HPGD (0.56) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL8040252 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTPOLBGAAHTT | |
| SCHEMBL8039185 | 0.76 | PYGL (0.49) | ALDH1A1MAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081892-A1 | NOVEL CATECHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THOSE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2009-07-02 | — | — | WO | disclosed |