Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044338 | 0.93 | POLB (0.44) | MAPTRAB9ALMNANPC1ALDH1A1 | |
| SCHEMBL8048046 | 0.91 | MAPT (0.47) | MAPTRAB9ALMNANPC1ALDH1A1 | |
| SCHEMBL8034092 | 0.88 | HTR1A (0.49) | MAPTRAB9ALMNANPC1ALDH1A1 | |
| SCHEMBL8033890 | 0.85 | RAB9A (0.46) | MAPTRAB9ALMNANPC1ALDH1A1 | |
| SCHEMBL8046628 | 0.84 | AR (0.40) | MAPTRAB9ALMNANPC1MEN1 | |
| SCHEMBL8051792 | 0.82 | AR (0.43) | MAPTRAB9ALMNANPC1KMT2A | |
| SCHEMBL8049804 | 0.81 | KMT2A (0.43) | MAPTRAB9ALMNANPC1ALDH1A1 | |
| SCHEMBL8043683 | 0.81 | HTR1A (0.47) | MAPTRAB9ALMNANPC1ALDH1A1 | |
| SCHEMBL8033941 | 0.79 | SMN1; SMN2 (0.36) | MAPTRAB9ALMNANPC1ALDH1A1 | |
| SCHEMBL8042670 | 0.79 | RAB9A (0.43) | MAPTRAB9ALMNANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |