Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042296 | 0.92 | RAB9A (0.39) | SMN1; SMN2MAPTPKMCYP1A2CYP3A4 | |
| SCHEMBL8043900 | 0.90 | SMN1; SMN2 (0.36) | SMN1; SMN2MAPTRAB9ANPC1POLB | |
| SCHEMBL8042050 | 0.82 | LMNA (0.42) | SMN1; SMN2MAPTPKMRAB9ANPC1 | |
| SCHEMBL8034092 | 0.81 | HTR1A (0.49) | SMN1; SMN2MAPTRAB9ANPC1GAA | |
| SCHEMBL8050096 | 0.80 | RAB9A (0.37) | SMN1; SMN2MAPTRAB9ANPC1POLB | |
| SCHEMBL8042402 | 0.80 | ALDH1A1 (0.40) | SMN1; SMN2MAPTRAB9ANPC1POLB | |
| SCHEMBL8044982 | 0.79 | MAPT (0.44) | SMN1; SMN2MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8044452 | 0.79 | RAB9A (0.44) | SMN1; SMN2MAPTPKMRAB9ANPC1 | |
| SCHEMBL8050333 | 0.78 | GABRA5 (0.40) | SMN1; SMN2MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8050993 | 0.77 | CTSS (0.36) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |