Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.80 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SI | P14410 | 1/20 | 0.52 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.48 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8045378 | 0.78 | KMT2A (0.70) | KCNMA1ATMALDH1A1LMNATP53 | |
| SCHEMBL20815428 | 0.78 | KCNMA1 (0.64) | KCNMA1ATMALDH1A1LMNATP53 | |
| SCHEMBL9302790 | 0.77 | HPGD (1.00) | KCNMA1ATMALDH1A1LMNATP53 | |
| SCHEMBL3552907 | 0.76 | KCNMA1 (0.67) | KCNMA1ATMALDH1A1LMNATP53 | |
| SCHEMBL9303187 | 0.76 | KCNMA1 (0.67) | KCNMA1ATMALDH1A1LMNATP53 | |
| SCHEMBL29839046 | 0.75 | KCNMA1 (0.69) | KCNMA1ATMALDH1A1LMNATP53 | |
| SCHEMBL16398499 | 0.73 | GRM2 (0.75) | KCNMA1LMNATP53SLC9A1GRM2 | |
| SCHEMBL13896899 | 0.73 | KCNMA1 (0.61) | KCNMA1ATMALDH1A1LMNATP53 | |
| SCHEMBL2734889 | 0.72 | GRM2 (1.00) | KCNMA1ALDH1A1SLC9A1GRM2TDP1 | |
| SCHEMBL260406 | 0.71 | SLC9A1 (0.66) | KCNMA1ATMTSHRSLC9A1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1010712-B1 | Aliphatic thermoplastic polyurethanes, a process for their preparation and their use | BAYER MATERIALSCIENCE AG (DE) | 2009-10-28 | — | — | EP | claimed |