Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042933 | 0.87 | DCUN1D1 (0.37) | RAB9AL3MBTL1NPC1PDPK1SMN1; SMN2 | |
| SCHEMBL8050943 | 0.79 | FBP1 (0.42) | SMN1; SMN2FBP1DCUN1D1 | |
| SCHEMBL8032624 | 0.79 | RAB9A (0.49) | RAB9AL3MBTL1NPC1CYP19A1SMN1; SMN2 | |
| SCHEMBL8044452 | 0.78 | RAB9A (0.44) | RAB9AL3MBTL1NPC1SMN1; SMN2GAA | |
| SCHEMBL8033963 | 0.78 | RAB9A (0.44) | RAB9AL3MBTL1NPC1CYP19A1SMN1; SMN2 | |
| SCHEMBL8051281 | 0.77 | MEN1 (0.39) | FBP1MGAMGAASIMGAM2 | |
| SCHEMBL8033274 | 0.77 | FBP1 (0.41) | RAB9ANPC1SMN1; SMN2FBP1DCUN1D1 | |
| SCHEMBL8052354 | 0.75 | L3MBTL1 (0.46) | RAB9AL3MBTL1NPC1FBP1MGAM | |
| SCHEMBL8051792 | 0.75 | AR (0.43) | RAB9AL3MBTL1NPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL8044818 | 0.75 | RAB9A (0.41) | RAB9ANPC1CYP19A1SMN1; SMN2FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |