Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042050 | 0.88 | LMNA (0.42) | RAB9AMEN1THRBKMT2ANPC1 | |
| SCHEMBL8032624 | 0.86 | RAB9A (0.49) | RAB9AL3MBTL1KMT2ANPC1ALDH1A1 | |
| SCHEMBL8043900 | 0.82 | SMN1; SMN2 (0.36) | RAB9AL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL8051792 | 0.81 | AR (0.43) | RAB9AL3MBTL1KMT2ANPC1LMNA | |
| SCHEMBL8044346 | 0.80 | LMNA (0.41) | RAB9AL3MBTL1NPC1ALDH1A1GAA | |
| SCHEMBL8033941 | 0.79 | SMN1; SMN2 (0.36) | RAB9AL3MBTL1MEN1KMT2ANPC1 | |
| SCHEMBL8045945 | 0.78 | RAB9A (0.46) | RAB9AL3MBTL1NPC1GAADCUN1D1 | |
| SCHEMBL8042402 | 0.78 | ALDH1A1 (0.40) | RAB9AL3MBTL1MEN1THRBKMT2A | |
| SCHEMBL8033189 | 0.77 | RAB9A (0.38) | RAB9AL3MBTL1MEN1THRBKMT2A | |
| SCHEMBL8052354 | 0.77 | L3MBTL1 (0.46) | RAB9AL3MBTL1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |