Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | USP8 | P40818 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.34 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034272 | 0.83 | ALDH1A1 (0.41) | USP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8032480 | 0.78 | PKM (0.38) | USP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8051217 | 0.78 | EIF4E (0.36) | KMT2AALDH1A1MEN1MAPTEIF4E | |
| SCHEMBL8044489 | 0.77 | PKM (0.38) | USP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8043961 | 0.77 | ALDH1A1 (0.42) | USP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8043682 | 0.76 | HTT (0.50) | USP2KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8033827 | 0.76 | TSHR (0.52) | USP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8032690 | 0.75 | KDM4E (0.45) | KMT2AALDH1A1MEN1MAPTLMNA | |
| SCHEMBL8044252 | 0.75 | ATM (0.41) | KMT2AALDH1A1EIF4EHTT | |
| SCHEMBL8044246 | 0.75 | ALDH1A1 (0.39) | USP2KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |