Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 3/20 | 0.44 |
| ▸ | VNN1 | O95497 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360246 | 0.87 | LSS (0.46) | LSSMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL8049755 | 0.86 | LSS (0.46) | LSSMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL8035630 | 0.86 | LSS (0.60) | LSSMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL8045307 | 0.86 | LSS (0.46) | LSSMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL8052792 | 0.83 | LSS (0.43) | LSSMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL8035335 | 0.82 | LSS (0.48) | LSSMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL8045026 | 0.78 | MAPT (0.48) | LSSMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL8047800 | 0.76 | ALDH1A1 (0.49) | LSSVNN1MAPTALDH1A1RAB9A | |
| SCHEMBL8905081 | 0.76 | ALDH1A1 (0.49) | LSSVNN1MAPTALDH1A1RAB9A | |
| SCHEMBL8035910 | 0.76 | VNN1 (0.46) | LSSVNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636367-B1 | Use of phenylalkylamines for producing cholesterol lowering agents | HOFFMANN LA ROCHE (CH) | 2000-03-29 | — | — | EP | claimed |