Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL780148 | 0.76 | TSHR (0.39) | CA12CA1CA2CA4CA7 | |
| SCHEMBL4877004 | 0.76 | CA1 (0.52) | CA12CA1CA2CA4CA7 | |
| SCHEMBL11653179 | 0.74 | ALDH1A1 (0.46) | CA12CA1CA2CA4CA7 | |
| SCHEMBL28056147 | 0.74 | NFE2L2 (0.37) | CA12CA1CA2CA4CA7 | |
| SCHEMBL11649447 | 0.74 | CA2 (0.46) | CA12CA1CA2CA4CA7 | |
| SCHEMBL11805356 | 0.74 | LMNA (0.38) | CA12CA1CA2CA4CA7 | |
| SCHEMBL11323265 | 0.71 | KDM4E (0.40) | — | |
| SCHEMBL471981 | 0.71 | SYK (0.39) | CA12CA2CA9 | |
| SCHEMBL11654148 | 0.71 | POLB (0.44) | — | |
| SCHEMBL28171688 | 0.71 | MAPT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046180-A | NAALADase inhibitors | GUILFORD PHARMACEUTICALS INC. (US) | 2000-04-04 | — | — | US | disclosed |