SCHEMBL8046829

SCHEMBL8046829

Cc1ccc(S(=O)(=O)c2ccc(-c3ccccc3C(=O)O)c(S(=O)(=O)c3ccc(C)c(C)c3)c2)cc1C

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.45
GAA P10253 2/20 0.45
PKM P14618 1/20 0.45
MYC P01106 1/20 0.43
KMT2A Q03164 3/20 0.41
POLB P06746 2/20 0.41
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 2/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HPGD P15428 1/20 0.41
CYP1A2 P05177 1/20 0.41
LMNA P02545 2/20 0.41
MEN1 O00255 2/20 0.41
PTGDR2 Q9Y5Y4 1/20 0.41
FOLH1 Q04609 1/20 0.40
GFER P55789 1/20 0.39
SFRP1 Q8N474 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8064306 0.88 ALDH1A1 (0.45) ALDH1A1GAAMYCKMT2APOLB
SCHEMBL8064348 0.86 POLB (0.43) ALDH1A1GAAMYCKMT2APOLB
SCHEMBL8046884 0.83 SLC16A1 (0.46) ALDH1A1KMT2APOLBMAPTHPGD
SCHEMBL8059442 0.82 ALDH1A1 (0.48) ALDH1A1GAAPKMMYCKMT2A
SCHEMBL8046836 0.77 ALDH1A1 (0.48) ALDH1A1GAAPKMKMT2APOLB
SCHEMBL8057539 0.77 MYC (0.46) ALDH1A1GAAMYCKMT2APOLB
SCHEMBL15606239 0.76 MYC (0.53) ALDH1A1GAAMYCKMT2APOLB
SCHEMBL8062016 0.73 ALDH1A1 (0.70) ALDH1A1GAAPKMKMT2APOLB
SCHEMBL8046908 0.73 ALDH1A1 (0.70) ALDH1A1GAAPKMKMT2APOLB
SCHEMBL10451409 0.73 ALDH1A1 (0.59) ALDH1A1GAAPKMKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed