SCHEMBL8064306

SCHEMBL8064306

Cc1ccc(S(=O)(=O)c2ccc(-c3ccccc3C(=O)O)c(S(=O)(=O)c3ccc(C)cc3)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
LMNA P02545 1/20 0.45
POLB P06746 3/20 0.44
GAA P10253 3/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MYC P01106 1/20 0.41
AKR1C3 P42330 1/20 0.41
SLC16A1 P53985 1/20 0.41
KMT2A Q03164 2/20 0.40
FOLH1 Q04609 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
APOBEC3A P31941 1/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8046829 0.88 ALDH1A1 (0.45) ALDH1A1LMNAPOLBGAASMN1; SMN2
SCHEMBL8064348 0.87 POLB (0.43) ALDH1A1LMNAPOLBGAAHTT
SCHEMBL8046884 0.86 SLC16A1 (0.46) ALDH1A1POLBSLC16A1KMT2AFOLH1
SCHEMBL8059453 0.82 GAA (0.47) ALDH1A1LMNAPOLBGAAHTT
SCHEMBL13908249 0.79 MMP2 (0.53) POLBGAAHTTSMN1; SMN2L3MBTL1
SCHEMBL8057539 0.78 MYC (0.46) ALDH1A1POLBGAAMYCKMT2A
SCHEMBL8064310 0.77 POLB (0.57) ALDH1A1POLBGAASMN1; SMN2L3MBTL1
SCHEMBL30901415 0.76 L3MBTL1 (0.44) ALDH1A1GAASMN1; SMN2L3MBTL1KMT2A
SCHEMBL8962291 0.75 APEX1 (0.60) ALDH1A1LMNAPOLBGAAHTT
SCHEMBL8061969 0.75 HTR6 (0.50) ALDH1A1POLBGAASMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed