SCHEMBL8046836

SCHEMBL8046836

Cc1ccc(S(=O)(=O)c2ccc(-c3ccc(C(=O)O)cc3)c(S(=O)(=O)c3ccc(C)c(C)c3)c2)cc1C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46
RXRA P19793 2/20 0.45
RXRB P28702 2/20 0.45
RXRG P48443 1/20 0.45
POLB P06746 4/20 0.44
GFER P55789 1/20 0.43
KMT2A Q03164 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.40
APEX1 P27695 1/20 0.40
CTDSP1 Q9GZU7 1/20 0.40
HSD17B13 Q7Z5P4 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.39
MCOLN3 Q8TDD5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8064310 0.88 POLB (0.57) ALDH1A1GAARXRARXRBRXRG
SCHEMBL8064351 0.86 HSD17B13 (0.46) ALDH1A1RXRARXRBRXRGPOLB
SCHEMBL8046887 0.82 ALDH1A1 (0.51) ALDH1A1RXRARXRBPOLBKMT2A
SCHEMBL8046829 0.77 ALDH1A1 (0.45) ALDH1A1GAAPKMPOLBGFER
SCHEMBL7821892 0.76 L3MBTL1 (0.68) ALDH1A1RXRARXRBRXRGPOLB
SCHEMBL8057544 0.74 RXRA (0.52) ALDH1A1GAAPKMRXRARXRB
SCHEMBL8059442 0.72 ALDH1A1 (0.48) ALDH1A1GAAPKMPOLBKMT2A
SCHEMBL47890 0.72 LMNA (0.67) ALDH1A1GAAPKMPOLBKMT2A
SCHEMBL8064234 0.71 ALDH1A1 (0.81) ALDH1A1GAAPKMPOLBGFER
SCHEMBL3234816 0.70 RXRA (0.62) ALDH1A1RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed