Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478340 | 0.78 | ALDH1A1 (0.40) | LMNAFGFR1MAPTHSD17B10L3MBTL1 | |
| SCHEMBL8044732 | 0.77 | KDM4E (0.52) | LMNAMKNK1MAPTCASP1CASP7 | |
| SCHEMBL7474146 | 0.77 | HPGD (0.59) | LMNAMAPTCASP1CASP7HSD17B10 | |
| SCHEMBL7485545 | 0.77 | ALDH1A1 (0.45) | PDE2ALMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL7473993 | 0.75 | ADORA3 (0.41) | MAPTHSD17B10KDM4EGAAHPGD | |
| SCHEMBL7476332 | 0.73 | ENPP1 (0.52) | MAPTKDM4EGAAHPGDHIF1A | |
| SCHEMBL7478966 | 0.70 | HSD17B10 (0.43) | PDE2ALMNAMAPTCASP1HSD17B10 | |
| SCHEMBL23122602 | 0.70 | LMNA (0.52) | LTA4HPDE2ALMNAMKNK1MAPT | |
| SCHEMBL28794833 | 0.68 | ASAH1 (0.55) | LMNAMAPTCASP1CASP7HSD17B10 | |
| SCHEMBL30098131 | 0.68 | ASAH1 (0.55) | LMNAMAPTCASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114537-A | 1,2,4-THIADIAZOLE COMPOUND IS USEFUL FOR TRAPPING THIOL COMPOUNDS AND SELECTIVELY CHANGING THIOLS TO DISULFIDE COMPOUNDS | APOTEX INC. (CA) | 2000-09-05 | — | — | US | disclosed |