SCHEMBL8046875

SCHEMBL8046875

CCCCOc1ccc(S(=O)(=O)c2ccccc2)cc1S(=O)(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 6/20 0.48
CCNE2 O96020 1/20 0.47
CCNE1 P24864 1/20 0.47
CDK2 P24941 1/20 0.47
ABCC1 P33527 4/20 0.47
TSHR P16473 2/20 0.46
ALDH1A1 P00352 2/20 0.46
WDR5 P61964 3/20 0.45
S1PR3 Q99500 1/20 0.44
SFRP1 Q8N474 2/20 0.43
HTR6 P50406 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8046994 0.93 SFRP1 (0.44) ABCB1CCNE2CCNE1CDK2ABCC1
SCHEMBL8058697 0.87 HTR6 (0.46) ABCB1ABCC1TSHRALDH1A1SFRP1
SCHEMBL9398222 0.85 HTR6 (0.60) ABCB1CCNE2CCNE1CDK2ABCC1
SCHEMBL8068208 0.82 GAA (0.55) ALDH1A1SFRP1HTR6GAAL3MBTL1
SCHEMBL9214247 0.81 HTR6 (0.58) ABCB1CCNE2CCNE1CDK2ABCC1
SCHEMBL931962 0.79 TSHR (0.55) ABCB1TSHRALDH1A1HTR6CA12
SCHEMBL8046997 0.79 HTR6 (0.69) TSHRALDH1A1SFRP1HTR6CA12
SCHEMBL8046905 0.78 MEN1 (0.46) S1PR3
SCHEMBL8747424 0.77 HTR6 (0.62) ABCB1CCNE2CCNE1CDK2ABCC1
SCHEMBL8710539 0.77 CCNE2 (0.53) ABCB1CCNE2CCNE1CDK2ABCC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed