SCHEMBL8058697

SCHEMBL8058697

CCOc1ccc(S(=O)(=O)c2ccccc2)cc1S(=O)(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.46
SFRP1 Q8N474 3/20 0.46
POLB P06746 4/20 0.45
MAPK1 P28482 3/20 0.44
RXFP1 Q9HBX9 1/20 0.44
LMNA P02545 1/20 0.44
RAB9A P51151 1/20 0.44
MAPT P10636 2/20 0.44
ALDH1A1 P00352 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ABCB1 P08183 1/20 0.44
ABCC1 P33527 1/20 0.44
NAMPT P43490 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TSHR P16473 4/20 0.42
GAA P10253 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8046994 0.88 SFRP1 (0.44) HTR6SFRP1POLBMAPK1MAPT
SCHEMBL8046875 0.87 ABCB1 (0.48) HTR6SFRP1POLBMAPTALDH1A1
SCHEMBL8057507 0.86 TSHR (0.53) POLBMAPK1LMNAMAPTALDH1A1
SCHEMBL7414743 0.84 HTT (0.53) HTR6SFRP1POLBLMNAMAPT
SCHEMBL18247354 0.83 HTR6 (0.66) HTR6RXFP1MAPTALDH1A1SMN1; SMN2
SCHEMBL8046997 0.82 HTR6 (0.69) HTR6SFRP1POLBMAPK1RXFP1
SCHEMBL7417562 0.81 TP53 (0.42) HTR6SFRP1POLBMAPK1LMNA
SCHEMBL8061999 0.81 ABCB1 (0.47) HTR6SFRP1POLBMAPK1MAPT
SCHEMBL8061991 0.80 HTR6 (0.45) HTR6POLBRXFP1LMNAMAPT
SCHEMBL8061989 0.80 HTR6 (0.45) HTR6POLBRXFP1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed