SCHEMBL8047157

SCHEMBL8047157

CC(OCCBr)Oc1ccc(CC#N)cc1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.35
FLT3 P36888 1/20 0.33
KMT2A Q03164 1/20 0.32
GHSR Q92847 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
GAA P10253 1/20 0.32
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28035017 0.77 PKM (0.40) PKMFLT3KMT2AGHSRL3MBTL1
SCHEMBL19781563 0.77 POLB (0.50) PKMKMT2AGAAPOLB
SCHEMBL4833131 0.75 KDM4E (0.39) PKMGAA
SCHEMBL6573779 0.74 PKM (0.40) PKMFLT3KMT2AGHSRL3MBTL1
Ethane SCHEMBL11166229 0.70 ACACB (0.40) PKMKMT2APOLB
SCHEMBL8047159 0.70 SMN1; SMN2 (0.49) PKMKMT2AL3MBTL1GAA
SCHEMBL349208 0.70 LMNA (0.42) PKMKMT2AL3MBTL1GAAPOLB
SCHEMBL31570130 0.69 ALDH3A1 (0.39) KMT2AL3MBTL1GAA
SCHEMBL28930709 0.68 PRMT1 (0.40) GAA
SCHEMBL11322784 0.68 KDM4E (0.36) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000229932-A AB2 POLYMERIZABLE COMPOUND HAVING ACTIVE METHYLENE TYPE OXYALKYLENE RESIDUE AND POLYALKYLENE OXIDE POLYBRANCHED POLYMER KAWAMURA INST OF CHEM RES 2000-08-22 JP disclosed