Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GHSR | Q92847 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781563 | 0.85 | POLB (0.50) | PKMKMT2APOLBGAACYP1A2 | |
| SCHEMBL6573779 | 0.81 | PKM (0.40) | PKMKMT2APOLBL3MBTL1GAA | |
| SCHEMBL14150418 | 0.78 | LTA4H (0.44) | POLBGAACYP1A2CYP2D6CYP2C19 | |
| Ethane SCHEMBL11166229 | 0.78 | ACACB (0.40) | PKMKMT2APOLBNPC1RAB9A | |
| SCHEMBL8047157 | 0.77 | PKM (0.35) | PKMKMT2APOLBL3MBTL1GAA | |
| SCHEMBL349208 | 0.77 | LMNA (0.42) | PKMKMT2APOLBL3MBTL1GAA | |
| SCHEMBL17911615 | 0.77 | ALDH1A3 (0.41) | PKMKMT2APOLBGAACYP1A2 | |
| SCHEMBL27473073 | 0.75 | L3MBTL1 (0.37) | PKMKMT2AL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL10953849 | 0.74 | MAPT (0.45) | PKMKMT2APOLBCYP2D6CYP2C19 | |
| 3-Methoxyphenylacetonitrile SCHEMBL103029 | 0.74 | PKM (0.61) | PKMKMT2APOLBGAAFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106103431-A | Hydroxycarboxamide derivatives and their use | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-104918922-A | TRIAZOLONE COMPOUNDS AND USES THEREOF | INCEPTION 2 INC | 2015-09-16 | — | — | CN | disclosed |