Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NMBR | P28336 | 4/20 | 0.37 |
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR1E | P28566 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20106639 | 0.86 | MDM4 (0.47) | MDM4TP53RENHTR1DHTR2C | |
| SCHEMBL30195150 | 0.86 | MDM4 (0.40) | MDM4TP53 | |
| SCHEMBL12982608 | 0.82 | MDM4 (0.42) | MDM4TP53 | |
| SCHEMBL30812609 | 0.78 | PIN1 (0.42) | MDM4TP53 | |
| SCHEMBL17269327 | 0.78 | MDM4 (0.56) | MDM4TP53 | |
| SCHEMBL30600490 | 0.78 | MDM4 (0.56) | MDM4TP53 | |
| SCHEMBL20677239 | 0.78 | MDM4 (0.56) | MDM4TP53 | |
| SCHEMBL28015870 | 0.78 | MDM4 (0.56) | MDM4TP53 | |
| SCHEMBL15164253 | 0.75 | MDM4 (0.48) | MDM4TP53HTR1DHTR2CHTR1E | |
| SCHEMBL27890071 | 0.74 | MDM4 (0.49) | MDM4TP53HTR1DHTR2CHTR1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732137-B2 | Semi-recombinant preparation of GLP-1 analogues | NOVO NORDISK A/S (DK) | 2017-08-15 | — | — | US | disclosed |
| US-9732137-B2 | Semi-recombinant preparation of GLP-1 analogues | NOVO NORDISK A/S (DK) | 2017-08-15 | — | — | US | disclosed |
| US-20100317057-A1 | SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES | NOVO NORDISK A/S (DK) | 2010-12-16 | — | — | US | disclosed |
| WO-2009083549-A1 | SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES | NOVO NORDISK A/S (DK) | 2009-07-09 | — | — | WO | disclosed |