Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044839 | 0.92 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1PRNPMEN1KMT2A | |
| SCHEMBL8047362 | 0.91 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1PRNPMEN1KMT2A | |
| SCHEMBL8045031 | 0.86 | MMP3 (0.45) | AHRPRNPALDH1A1 | |
| SCHEMBL8052660 | 0.86 | PPARG (0.43) | CYSLTR2CYSLTR1PPARGALDH1A1KDM4E | |
| SCHEMBL8047275 | 0.85 | AHR (0.39) | AHRPRNPMEN1KMT2AALDH1A1 | |
| SCHEMBL8045896 | 0.84 | CCR1 (0.41) | KMT2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL8046467 | 0.84 | CCR1 (0.41) | KMT2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL8046084 | 0.82 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1PRNPMEN1KMT2A | |
| SCHEMBL8035061 | 0.81 | AHR (0.39) | CYSLTR2CYSLTR1AHRPRNPMEN1 | |
| SCHEMBL8049892 | 0.77 | OPRM1 (0.48) | ALDH1A1TOP2ASMN1; SMN2CCR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |