Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044839 | 0.86 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1MEN1KMT2APRNP | |
| SCHEMBL8045910 | 0.85 | HDAC1 (0.35) | NPC1RAB9AALDH1A1MAPTLMNA | |
| SCHEMBL8052937 | 0.84 | HDAC1 (0.48) | — | |
| SCHEMBL8047362 | 0.83 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1MEN1KMT2APRNP | |
| SCHEMBL8049575 | 0.82 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1MEN1KMT2APRNP | |
| SCHEMBL8052938 | 0.80 | HDAC1 (0.35) | CYSLTR2CYSLTR1KDM4E | |
| SCHEMBL8892532 | 0.74 | OPRM1 (0.42) | MEN1KMT2ARAB9ARXFP1KDM4E | |
| SCHEMBL8049892 | 0.72 | OPRM1 (0.48) | TOP2AALDH1A1FAAHCYP4F2CYP4A11 | |
| SCHEMBL8044856 | 0.72 | OPRM1 (0.48) | TOP2AALDH1A1FAAHCYP4F2CYP4A11 | |
| SCHEMBL8035390 | 0.71 | L3MBTL1 (0.45) | MEN1KMT2ATOP2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |