Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP8 | P40818 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PRUNE1 | Q86TP1 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401814 | 0.81 | — | — | |
| SCHEMBL194427 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2POLBTDP1ALDH1A1TSHR | |
| SCHEMBL8047514 | 0.77 | — | — | |
| SCHEMBL6243535 | 0.77 | MAPT (0.44) | SMN1; SMN2POLBTDP1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL8038931 | 0.75 | MAPT (0.43) | SMN1; SMN2POLBTDP1ALDH1A1TSHR | |
| SCHEMBL107407 | 0.75 | PRUNE1 (0.47) | SMN1; SMN2ALDH1A1TSHRKMT2AMAPT | |
| SCHEMBL13893832 | 0.74 | SMN1; SMN2 (0.36) | SMN1; SMN2POLBTDP1ALDH1A1TSHR | |
| SCHEMBL8142070 | 0.72 | CA2 (0.32) | — | |
| SCHEMBL8615220 | 0.72 | NQO1 (0.54) | SMN1; SMN2POLBTDP1ALDH1A1TSHR | |
| SCHEMBL27220454 | 0.72 | LTA4H (0.52) | SMN1; SMN2ALDH1A1TSHRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799193-B1 | HIGH PURITY N-(4-[N,N-BIS(2-IODOETHYL)AMINO]PHENOSCYCARBONYL)-L-GLUTAMIC ACID | ZENECA LTD (GB) | 2000-08-16 | — | — | EP | disclosed |