Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8047188 | 0.87 | MEN1 (0.53) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL8050622 | 0.85 | MEN1 (0.40) | RECQLMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL8033896 | 0.84 | NPC1 (0.54) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL8048230 | 0.84 | KDM4E (0.43) | RECQLMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL8043113 | 0.84 | RAB9A (0.48) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL8050800 | 0.82 | HTR1A (0.49) | RECQLKMT2AKDM4ENPC1RAB9A | |
| SCHEMBL8046882 | 0.80 | RECQL (0.41) | RECQLMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL8047015 | 0.79 | RECQL (0.52) | RECQLMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL8043598 | 0.79 | RECQL (0.55) | RECQLMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8044774 | 0.78 | KDM4E (0.43) | RECQLMEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |