Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033896 | 0.85 | NPC1 (0.54) | RAB9AUSP2ALDH1A1MAPTKDM4E | |
| SCHEMBL8048032 | 0.84 | RECQL (0.41) | RAB9ACPB1HPGDALDH1A1MAPT | |
| SCHEMBL8047188 | 0.84 | MEN1 (0.53) | RAB9AHPGDALDH1A1MAPTKDM4E | |
| SCHEMBL8033238 | 0.83 | RAB9A (0.52) | RAB9ACPB1HPGDUSP2ALDH1A1 | |
| SCHEMBL8043598 | 0.83 | RECQL (0.55) | HPGDUSP2ALDH1A1MAPTKDM4E | |
| SCHEMBL8041907 | 0.82 | RAB9A (0.47) | RAB9ACPB1HPGDUSP2ALDH1A1 | |
| SCHEMBL8050622 | 0.82 | MEN1 (0.40) | RAB9ACPB1HPGDUSP2ALDH1A1 | |
| SCHEMBL8043119 | 0.79 | ALDH1A1 (0.48) | RAB9AHPGDUSP2ALDH1A1MAPT | |
| SCHEMBL8041830 | 0.78 | CPB1 (0.47) | RAB9ACPB1HPGDUSP2ALDH1A1 | |
| SCHEMBL8042512 | 0.78 | RAB9A (0.50) | RAB9ACPB1HPGDUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |