Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | TSHR | P16473 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033852 | 0.86 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL8048338 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRLMNAMAPK1NPSR1 | |
| SCHEMBL8042693 | 0.82 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPK1HTTMEN1 | |
| SCHEMBL8045327 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPK1NPSR1HTT | |
| SCHEMBL8032728 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TSHRLMNAMAPK1NPSR1 | |
| SCHEMBL8052246 | 0.78 | KMT2A (0.36) | ALDH1A1LMNAMAPK1ALOX15NPSR1 | |
| SCHEMBL8051135 | 0.77 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL8032682 | 0.77 | TSHR (0.45) | L3MBTL1ALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL8048145 | 0.76 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL8032337 | 0.76 | HTT (0.39) | ALDH1A1TSHRLMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |