Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048416 | 0.85 | ALDH1A1 (0.40) | HTTLMNAMAPTCYP3A4CYP1A2 | |
| SCHEMBL8048446 | 0.85 | ALDH1A1 (0.42) | HTTLMNAMAPTCYP3A4CYP1A2 | |
| SCHEMBL8060054 | 0.84 | ALDH1A1 (0.38) | HTTLMNAMAPTCYP3A4CYP1A2 | |
| SCHEMBL8065523 | 0.83 | KDM4E (0.35) | HTTLMNAMAPTCYP3A4CYP1A2 | |
| SCHEMBL7527475 | 0.82 | HSD11B1 (0.38) | HTTLMNAMAPTCYP3A4CYP1A2 | |
| SCHEMBL8065549 | 0.80 | MEN1 (0.49) | HTTLMNAMAPTCYP3A4CYP1A2 | |
| SCHEMBL8058977 | 0.80 | ALDH1A1 (0.51) | HTTLMNAMAPTALDH1A1HPGD | |
| SCHEMBL8065524 | 0.79 | MAPK8 (0.36) | HTTLMNAALDH1A1GAASMN1; SMN2 | |
| Zoxamide SCHEMBL170285 | 0.78 | LMNA (0.36) | HTTLMNAMAPTCYP3A4CYP1A2 | |
| Zoxamide SCHEMBL70113 | 0.78 | LMNA (0.36) | HTTLMNAMAPTCYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816331-B1 | Fungicidally active n-acetonylbenzamide compounds | ROHM & HAAS (US) | 2000-05-24 | — | — | EP | disclosed |
| US-5929098-A | Fungicidically active N-acetonylbenzamide compounds | ROHM AND HAAS COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0816331-A1 | Fungicidally active n-acetonylbenzamide compounds | ROHM AND HAAS COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |