SCHEMBL8048416

SCHEMBL8048416

CCC(C)(NC(=O)c1cc(N)c(Cl)c([N+](=O)[O-])c1)C(=O)CCl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
HSP90AA1 P07900 2/20 0.40
HPGD P15428 2/20 0.40
MAPT P10636 3/20 0.37
LMNA P02545 3/20 0.37
HTT P42858 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
GPR55 Q9Y2T6 1/20 0.37
GAA P10253 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPK1 P28482 1/20 0.34
HCAR3 P49019 1/20 0.34
ADRB2 P07550 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8060054 0.90 ALDH1A1 (0.38) ALDH1A1HSP90AA1HPGDMAPTLMNA
SCHEMBL8048446 0.86 ALDH1A1 (0.42) ALDH1A1HSP90AA1HPGDMAPTLMNA
SCHEMBL8048407 0.85 HTT (0.39) ALDH1A1HSP90AA1HPGDMAPTLMNA
SCHEMBL8065549 0.85 MEN1 (0.49) ALDH1A1HSP90AA1HPGDMAPTLMNA
SCHEMBL8061116 0.82 LMNA (0.31) ALDH1A1LMNAHTTSMN1; SMN2MEN1
SCHEMBL8058977 0.81 ALDH1A1 (0.51) ALDH1A1HPGDMAPTLMNAHTT
SCHEMBL8065523 0.80 KDM4E (0.35) ALDH1A1MAPTLMNAHTTCYP1A2
SCHEMBL8060039 0.80 HTT (0.31) HTT
SCHEMBL7527475 0.78 HSD11B1 (0.38) ALDH1A1MAPTLMNAHTTCYP1A2
SCHEMBL8058888 0.77 HTT (0.31) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0816331-B1 Fungicidally active n-acetonylbenzamide compounds ROHM & HAAS (US) 2000-05-24 EP disclosed
US-5929098-A Fungicidically active N-acetonylbenzamide compounds ROHM AND HAAS COMPANY (US) 1999-07-27 US disclosed
EP-0816331-A1 Fungicidally active n-acetonylbenzamide compounds ROHM AND HAAS COMPANY (US) 1998-01-07 EP disclosed