Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032670 | 0.88 | ALDH1A1 (0.51) | CYP3A4CYP1A2CYP2C19HPGDALDH1A1 | |
| SCHEMBL8034295 | 0.84 | NPC1 (0.42) | L3MBTL1ALDH1A1RAB9AHTTMEN1 | |
| SCHEMBL8042762 | 0.84 | NPC1 (0.41) | ALOX15HPGDALDH1A1TSHRLMNA | |
| SCHEMBL8041828 | 0.84 | ALDH1A1 (0.41) | CYP3A4CYP1A2CYP2D6CYP2C19ALOX15 | |
| SCHEMBL8042886 | 0.83 | KDM4E (0.44) | ALOX15HPGDALDH1A1TSHRLMNA | |
| SCHEMBL8045074 | 0.82 | RAB9A (0.41) | HPGDALDH1A1TSHRLMNARAB9A | |
| SCHEMBL8044652 | 0.81 | L3MBTL1 (0.41) | L3MBTL1CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL8033862 | 0.81 | POLB (0.47) | CYP2C19HPGDALDH1A1TSHRLMNA | |
| SCHEMBL8050828 | 0.80 | ALDH1A1 (0.48) | HPGDALDH1A1TSHRLMNAHTT | |
| SCHEMBL8050177 | 0.79 | ALDH1A1 (0.47) | ALOX15HPGDALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |