Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046383 | 0.91 | CYP4F2 (0.40) | CYP4F2CYP4A11KCNA3OPRM1ALDH1A1 | |
| SCHEMBL8053206 | 0.89 | FAAH (0.44) | CYP4F2CYP4A11KMT2AKCNA3OPRM1 | |
| SCHEMBL8049892 | 0.88 | OPRM1 (0.48) | CYP4F2CYP4A11KCNA3OPRM1ALDH1A1 | |
| SCHEMBL8044856 | 0.88 | OPRM1 (0.48) | CYP4F2CYP4A11KCNA3OPRM1ALDH1A1 | |
| SCHEMBL8046467 | 0.88 | CCR1 (0.41) | CYP4F2CYP4A11KMT2AKCNA3OPRM1 | |
| SCHEMBL8045896 | 0.88 | CCR1 (0.41) | CYP4F2CYP4A11KMT2AKCNA3OPRM1 | |
| SCHEMBL8046393 | 0.88 | L3MBTL1 (0.44) | CYP4F2CYP4A11ALDH1A1HSD17B10MAOB | |
| SCHEMBL8046235 | 0.87 | OPRM1 (0.49) | CYP4F2CYP4A11KCNA3OPRM1ALDH1A1 | |
| SCHEMBL8047298 | 0.84 | OPRM1 (0.44) | CYP4F2CYP4A11KCNA3OPRM1ALDH1A1 | |
| SCHEMBL8044912 | 0.84 | POLB (0.36) | CYP4F2CYP4A11KMT2AKCNA3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |