Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044653 | 0.74 | BACE1 (0.35) | — | |
| SCHEMBL8043935 | 0.69 | RXRA (0.33) | — | |
| SCHEMBL8044128 | 0.68 | — | — | |
| SCHEMBL8042073 | 0.67 | MAPT (0.43) | — | |
| SCHEMBL8033667 | 0.64 | — | — | |
| SCHEMBL8034315 | 0.64 | MMP12 (0.32) | — | |
| SCHEMBL578021 | 0.64 | TSHR (0.38) | ALDH1A1GFERRXFP1TSHR | |
| SCHEMBL463754 | 0.63 | TSHR (0.73) | ALDH1A1GFERRXFP1TSHR | |
| SCHEMBL8043101 | 0.63 | — | — | |
| SCHEMBL8045800 | 0.62 | DAO (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |