Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SI | P14410 | 3/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.47 |
| ▸ | SNCA | P37840 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13297688 | 0.86 | GUSB (0.49) | GAAGUSBHPGDMAPTHTT | |
| SCHEMBL8043597 | 0.80 | MGAM (0.40) | MGAMGAASIMGAM2GUSB | |
| SCHEMBL8043262 | 0.77 | GABRA1 (0.52) | MGAMGAASIMGAM2SNCA | |
| SCHEMBL22469017 | 0.75 | GUSB (0.46) | MGAMGAASIMGAM2IDO1 | |
| SCHEMBL27991140 | 0.71 | ALOX15 (0.62) | MGAMGAASIMGAM2IDO1 | |
| SCHEMBL8743338 | 0.71 | ALOX15 (0.62) | MGAMGAASIMGAM2IDO1 | |
| SCHEMBL8047389 | 0.71 | CA1 (0.49) | MGAMGAASIMGAM2SNCA | |
| SCHEMBL9179420 | 0.70 | SNCA (0.75) | SNCAGUSBMAPT | |
| SCHEMBL8045495 | 0.69 | HDAC1 (0.46) | GAAIDO1HPGDKDM4ETSHR | |
| SCHEMBL8046899 | 0.68 | HDAC1 (0.43) | GAAIDO1ALOX15HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |