Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17236450 | 0.86 | ORAI1 (0.55) | ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL17236459 | 0.83 | ENPP2 (0.52) | ORAI1ORAI2ORAI3TRPV6ENPP2 | |
| SCHEMBL17236457 | 0.83 | CA2 (0.52) | ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL1032149 | 0.81 | — | — | |
| SCHEMBL28014126 | 0.78 | TRPV6 (0.61) | ORAI1ORAI2ORAI3TRPV6MGLL | |
| SCHEMBL17236463 | 0.76 | KDM4E (0.58) | — | |
| SCHEMBL17236466 | 0.76 | TSHR (0.43) | ENPP2 | |
| SCHEMBL28199741 | 0.75 | — | — | |
| SCHEMBL17868174 | 0.62 | ORAI1 (0.55) | ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL1493119 | 0.62 | CA12 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057078-A | PHOTOGRAPHY | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |
| US-5807905-A | POLYMERIZATION OF UNSATURATED COMPOUNDS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-09-15 | — | — | US | disclosed |