Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962787 | 0.95 | HTR6 (0.31) | KMT2ATHRBMEN1DPP4 | |
| SCHEMBL7870406 | 0.95 | HTR6 (0.31) | KMT2ATHRBMEN1DPP4 | |
| SCHEMBL729174 | 0.95 | HTR6 (0.31) | KMT2ATHRBMEN1DPP4 | |
| SCHEMBL8146446 | 0.72 | HTR6 (0.47) | — | |
| SCHEMBL11735212 | 0.70 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2KMT2ACYP3A4CYP2C9 | |
| SCHEMBL5872327 | 0.70 | HRH3 (0.38) | ALDH1A1SMN1; SMN2KMT2ACYP3A4CYP2C9 | |
| SCHEMBL10721919 | 0.70 | EPHX1 (0.33) | ALDH1A1SMN1; SMN2KMT2ACYP3A4CYP2C9 | |
| SCHEMBL3246436 | 0.70 | EPHX1 (0.33) | ALDH1A1SMN1; SMN2KMT2ACYP3A4CYP2C9 | |
| SCHEMBL10721961 | 0.70 | EPHX1 (0.33) | ALDH1A1SMN1; SMN2KMT2ACYP3A4CYP2C9 | |
| SCHEMBL7019251 | 0.70 | EPHX1 (0.33) | ALDH1A1SMN1; SMN2KMT2ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080760-A | TREATING BENIGN PROSTATIC HYPERPLASIA; COMPLEMENT SLOWER-ACTING THERAPEUTICS BY PROVIDING ACUTE RELIEF; INDUCE RELAXATION OF THE LOWER URINARY TRACT TO DECREASE DIFFICULTY IN URINATION AND SEXUAL DYSFUNCTION | MERCK & CO., INC. (US) | 2000-06-27 | — | — | US | disclosed |
| EP-1003511-A1 | ALPHA 1aADRENERGIC RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1998057639-A1 | ALPHA 1aADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1998-12-23 | — | — | WO | disclosed |
| US-4041032-A | ANTIEMATICS, GASTRIC MOTILITY STIMULANTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1977-08-09 | — | — | US | disclosed |