SCHEMBL8054041

SCHEMBL8054041

C[S+]([O-])c1ccccc1C(=O)Nc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.57
ALDH1A1 P00352 2/20 0.56
MEN1 O00255 7/20 0.54
KMT2A Q03164 7/20 0.54
KDM4E B2RXH2 1/20 0.54
LMNA P02545 1/20 0.54
TP53 P04637 1/20 0.54
HTT P42858 1/20 0.54
HSD17B10 Q99714 1/20 0.54
TDP1 Q9NUW8 3/20 0.53
METAP2 P50579 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
ALOX12 P18054 1/20 0.51
CHRNB2 P17787 1/20 0.51
CHRNB4 P30926 1/20 0.51
CHRNA3 P32297 1/20 0.51
CHRNA4 P43681 1/20 0.51
BCAT2 O15382 2/20 0.51
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8054126 0.89 RAB9A (0.60) HPGDALDH1A1MEN1KMT2AKDM4E
SCHEMBL6816336 0.88 KMT2A (0.47) HPGDALDH1A1MEN1KMT2ALMNA
SCHEMBL7079581 0.84 ACHE (0.45) HPGDALDH1A1MEN1KMT2AKDM4E
SCHEMBL7217674 0.83 HPGD (0.53) HPGDALDH1A1MEN1KMT2AKDM4E
SCHEMBL8042309 0.83 HPGD (0.53) HPGDALDH1A1MEN1KMT2AKDM4E
SCHEMBL6919153 0.82 NAMPT (0.47) HPGDMEN1KMT2AKDM4ELMNA
SCHEMBL25217438 0.79 CTSD (0.50) ALDH1A1MEN1KMT2AKDM4EHTT
SCHEMBL3308292 0.78 ALDH1A1 (0.52) HPGDALDH1A1KDM4EHSD17B10TDP1
Benzene SCHEMBL7833403 0.78 ALDH1A1 (0.52) HPGDALDH1A1KDM4EHSD17B10TDP1
SCHEMBL10451264 0.78 ALDH1A1 (0.52) HPGDALDH1A1KDM4EHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0751123-B1 Method for producing alkylsulfinylbenzamides SUMITOMO SEIKA CHEMICALS (JP) 2000-05-10 EP claimed
CN-1215721-A Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 1999-05-05 CN claimed
US-5744609-A REACTING AN ALKYLTHIOBENZAMIDE WITH A HALOGEN IN A HETEROGENOUS SOLVENT TO GIVE ALKYLSULFURYLBENZAMIDES INTERMEDIATES; USEFUL ANTIBACTERIAL AND ANTIFUNGAL AGENT SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-04-28 US claimed
EP-0751123-A2 Method for producing alkylsulfinylbenzamides SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-01-02 EP claimed
CN-1107837-A Process for producing alkylsulfinylbenzamides and 1, 2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 1995-09-06 CN claimed
EP-0657438-A2 Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1995-06-14 EP claimed
CN-1086693-C Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICAL CO LTD (JP) 2002-06-26 CN disclosed
EP-0751123-B1 Method for producing alkylsulfinylbenzamides SUMITOMO SEIKA CHEMICALS (JP) 2000-05-10 EP disclosed
CN-1215721-A Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 1999-05-05 CN disclosed
CN-1215722-A Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 1999-05-05 CN disclosed
CN-1042530-C Process for producing alkylsulfinylbenzamides SUMITOMO SEIKA CHEMICALS (JP) 1999-03-17 CN disclosed
US-5744609-A REACTING AN ALKYLTHIOBENZAMIDE WITH A HALOGEN IN A HETEROGENOUS SOLVENT TO GIVE ALKYLSULFURYLBENZAMIDES INTERMEDIATES; USEFUL ANTIBACTERIAL AND ANTIFUNGAL AGENT SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-04-28 US disclosed
US-5672751-A TREATMENT OF A HALOBENZAMIDE WITH AN ALKANETHIOL IN THE PRESENCE OF A PHASE TRANSFER CATALYST SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-09-30 US disclosed
EP-0751123-A2 Method for producing alkylsulfinylbenzamides SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-01-02 EP disclosed
US-5508416-A HALOGENATING A 2-(ALKYLTHIO)BENZAMIDE, CYCLIZATION TO HETERO RING AND N-S LINKAGE SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1996-04-16 US disclosed
CN-1107837-A Process for producing alkylsulfinylbenzamides and 1, 2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS (JP) 1995-09-06 CN disclosed
EP-0657438-A2 Method for producing alkylsulfinylbenzamides and 1,2-benzisothiazol-3-ones SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1995-06-14 EP disclosed