Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19033731 | 0.94 | SPHK1 (0.51) | SPHK1KDM1AMAOBSLC18A3ESR2 | |
| SCHEMBL8594527 | 0.94 | SPHK1 (0.51) | SPHK1KDM1AMAOBSLC18A3ESR2 | |
| Hydrochloric Acid SCHEMBL11831674 | 0.92 | SPHK1 (0.50) | SPHK1KDM1AMAOBSLC18A3ESR2 | |
| SCHEMBL1405569 | 0.82 | ESR2 (0.50) | SLC18A3ESR2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL734536 | 0.82 | MAOB (0.42) | SPHK1KDM1AMAOBSLC18A3ESR2 | |
| SCHEMBL17666384 | 0.82 | ESR2 (0.59) | SLC18A3ESR2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL12463654 | 0.82 | MAOB (0.42) | SPHK1KDM1AMAOBSLC18A3ESR2 | |
| SCHEMBL13476556 | 0.82 | MAOB (0.42) | SPHK1KDM1AMAOBSLC18A3ESR2 | |
| SCHEMBL10598069 | 0.82 | SMN1; SMN2 (0.49) | SLC18A3ESR2SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4428038 | 0.80 | ESR2 (0.59) | SLC18A3ESR2SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265345-A1 | LIQUID CRYSTAL COMPOSITION CONTAINING POLYMERIZABLE COMPOUND AND APPLICATION OF LIQUID CRYSTAL COMPOSITION | BEIJING BAYI SPACE LCD TECHNOLOGY CO., LTD. (CN) | 2023-08-24 | — | — | US | disclosed |
| WO-2023110962-A1 | LIQUID-CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |
| US-9809748-B2 | Liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-9776952-B2 | Polymerisable compounds and the use thereof in liquid-crystal media and liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-10-03 | — | — | US | disclosed |
| US-9650573-B2 | Liquid crystalline medium and liquid crystal device | MERCK PATENT GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| US-20170121606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | GMBH, MERCK PATENT (DE) | 2017-05-04 | — | — | US | disclosed |
| US-20170037316-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-09 | — | — | US | disclosed |
| US-20130037745-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-02-14 | — | — | US | disclosed |
| US-8349415-B2 | Liquid-crystalline medium and liquid-crystal display having high twist | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2013-01-08 | — | — | US | disclosed |
| US-20120327357-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-27 | — | — | US | disclosed |
| US-20080277623-A1 | Liquid Crystalline Medium | MERCK PATENT GMBH (DE) | 2008-11-13 | — | — | US | disclosed |
| US-7442419-B2 | Comprising one or more dielectrically positive compounds having a dielectric anisotropy of more than 3; twisted Nematic (TN) or Plane Switching (IPS) type; low rotational viscosity; polycyclo cyclohexyl fluorocarbon benzyl ether derivatives, electrooptics | MERCK PATENT GMBH (DE) | 2008-10-28 | — | — | US | disclosed |
| US-20080260971-A1 | Liquid-Crystalline Medium and Liquid-Crystal Display Comprising 1,2-Difluoroethene Compounds | MERCK PATENT GMBH (DE) | 2008-10-23 | — | — | US | disclosed |
| US-7438956-B2 | Liquid-crystalline medium and liquid-crystal display | MERCK PATENT GMBH (DE) | 2008-10-21 | — | — | US | disclosed |
| US-7419706-B2 | Liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-09-02 | — | — | US | disclosed |
| US-7419705-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2008-09-02 | — | — | US | disclosed |
| US-20080167482-A1 | mesogenic group is linked to the C-atom No. 5 of the 1,3-dioxane-5-yl group; media showing a blue phase and their use in electro-optical light modulation elements | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| US-20080128653-A1 | Liquid Crystalline Medium | MERCK PATENT GMBH (DE) | 2008-06-05 | — | — | US | disclosed |
| US-20080116419-A1 | Mesogenic Compounds, Liquid Crystal Medium and Liquid Crystal Display | MERCK PATENT GMBH (DE) | 2008-05-22 | — | — | US | disclosed |
| US-20070034830-A1 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications. | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170037316-A1 | LIQUID-CRYSTALLINE MEDIUM | FES, NEFM, SOST | SPHK1 3754/4885KDM1A 3440/4885MAOB 1313/4885 |
| US-20170121606-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, LCP1, MAP1LC3C | SPHK1 2180/4885KDM1A 4007/4885MAOB 3028/4885 |
| US-20080277623-A1 | Liquid Crystalline Medium | CHRM1, NEFM, CCNT1 | SPHK1 2489/4885KDM1A 4274/4885MAOB 2858/4885 |
| US-20080260971-A1 | Liquid-Crystalline Medium and Liquid-Crystal Display Comprising 1,2-Difluoroethene Compounds | CFL1, NEFM, CHRM1 | SPHK1 1301/4885KDM1A 3955/4885MAOB 1686/4885 |
| US-20120327357-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL MEDIA AND LIQUID-CRYSTAL DISPLAYS | LPXN, VCL, MAP1LC3C | SPHK1 1594/4885KDM1A 3707/4885MAOB 2004/4885 |
| US-20080116419-A1 | Mesogenic Compounds, Liquid Crystal Medium and Liquid Crystal Display | CRY1, CRY2, IK | SPHK1 3150/4885KDM1A 3592/4885MAOB 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.