Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 4/20 | 0.90 | |
| ▸ | MMP2 | P08253 | 14/20 | 0.72 |
| ▸ | MMP3 | P08254 | 12/20 | 0.72 |
| ▸ | MMP1 | P03956 | 10/20 | 0.72 |
| ▸ | MMP7 | P09237 | 4/20 | 0.72 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400277 | 1.00 | PDF (0.90) | PDFMMP2MMP3MMP1MMP7 | |
| SCHEMBL8397183 | 0.87 | PDF (0.90) | PDFMMP2MMP3MMP1MMP7 | |
| SCHEMBL8060154 | 0.86 | MMP2 (0.76) | PDFMMP2MMP3MMP1MMP7 | |
| SCHEMBL8060175 | 0.84 | MMP3 (1.00) | PDFMMP2MMP3MMP1MMP7 | |
| SCHEMBL8042125 | 0.84 | MMP3 (1.00) | PDFMMP2MMP3MMP1MMP7 | |
| SCHEMBL8054978 | 0.84 | MMP3 (1.00) | PDFMMP2MMP3MMP1MMP7 | |
| SCHEMBL8055018 | 0.83 | MMP3 (0.78) | PDFMMP2MMP3MMP1MMP7 | |
| SCHEMBL8042121 | 0.83 | MMP2 (0.78) | PDFMMP2MMP3MMP1MMP7 | |
| SCHEMBL4812129 | 0.82 | PDF (1.00) | PDFMMP2MMP3MMP1MMP7 | |
| SCHEMBL14282155 | 0.80 | PDF (0.73) | PDFMMP2MMP3MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028110-A | Succinyl hydroxamic acid, N-formyl-N-hydroxy amino carboxylic acid and succinic acid amide derivatives as metalloprotease inhibitors | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2000-02-22 | — | — | US | claimed |
| EP-0763012-B1 | SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1999-06-09 | — | — | EP | claimed |
| US-6028110-A | Succinyl hydroxamic acid, N-formyl-N-hydroxy amino carboxylic acid and succinic acid amide derivatives as metalloprotease inhibitors | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2000-02-22 | — | — | US | disclosed |
| EP-0763012-B1 | SUCCINYL HYDROXAMIC ACID, N-FORMYL-N-HYDROXY AMINO CARBOXYLIC ACID AND SUCCINIC ACID AMIDE DERIVATIVES AS METALLOPROTEASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1999-06-09 | — | — | EP | disclosed |