Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 4/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060260 | 0.90 | ESR1 (0.40) | SERPINE1ESR1PTPN1PTPN2PTPN11 | |
| SCHEMBL8057763 | 0.86 | ESR1 (0.38) | ESR1PTPN1PTPN2PTPN11TTR | |
| SCHEMBL8532176 | 0.81 | ESR1 (0.42) | SERPINE1ESR1PTPN1PTPN2PTPN11 | |
| SCHEMBL31668175 | 0.80 | TTR (0.48) | ESR1PTPN1PTPN2PTPN11TTR | |
| SCHEMBL31668196 | 0.79 | TTR (0.51) | ESR1TTRLMNAL3MBTL1KDM4E | |
| SCHEMBL8055952 | 0.79 | AKR1C4 (0.42) | SERPINE1ESR1PTPN1PTPN2PTPN11 | |
| SCHEMBL31668207 | 0.74 | TTR (0.50) | TTRLMNAKDM4EKMT2AAKR1C4 | |
| SCHEMBL22868140 | 0.74 | L3MBTL1 (0.48) | SERPINE1ESR1LMNAL3MBTL1KMT2A | |
| SCHEMBL6053862 | 0.70 | CYP3A4 (0.43) | TTRLMNAKMT2AAKR1C4AKR1C3 | |
| SCHEMBL1122760 | 0.69 | HCAR2 (0.43) | TTRLMNAKMT2AAKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785920-B1 | MULTIFUNCTIONAL CROSS-LINKING REAGENTS FOR HEMOGLOBIN, AND CROSS-LINKED HEMOGLOBIN CONJUGATES | KLUGER RONALD (CA) | 2000-05-17 | — | — | EP | claimed |
| EP-0785920-B1 | MULTIFUNCTIONAL CROSS-LINKING REAGENTS FOR HEMOGLOBIN, AND CROSS-LINKED HEMOGLOBIN CONJUGATES | KLUGER RONALD (CA) | 2000-05-17 | — | — | EP | disclosed |
| EP-0785920-A1 | MULTIFUNCTIONAL CROSS-LINKING REAGENTS FOR HEMOGLOBIN, AND CROSS-LINKED HEMOGLOBIN CONJUGATES | KLUGER, Ronald (CA) | 1997-07-30 | — | — | EP | disclosed |
| WO-1997000236-A1 | MULTIFUNCTIONAL CROSS-LINKING REAGENTS FOR HEMOGLOBIN, AND CROSS-LINKED HEMOGLOBIN CONJUGATES | KLUGER RONALD (CA) | 1997-01-03 | — | — | WO | disclosed |