SCHEMBL31668175

SCHEMBL31668175

O=C(OCc1cc(Br)cc(Br)c1O)c1ccc(C(=O)OCc2cc(Br)cc(Br)c2O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.48
KMT2A Q03164 6/20 0.46
MEN1 O00255 4/20 0.46
MAPT P10636 6/20 0.45
RAB9A P51151 2/20 0.45
POLB P06746 2/20 0.45
PKM P14618 1/20 0.45
CYBB P04839 1/20 0.43
LMNA P02545 2/20 0.42
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 3/20 0.42
HPGD P15428 2/20 0.42
ESR1 P03372 3/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
ESR2 Q92731 1/20 0.42
CA14 Q9ULX7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31668196 0.89 TTR (0.51) TTRKMT2AMAPTRAB9APOLB
SCHEMBL8532176 0.86 ESR1 (0.42) TTRKMT2AMEN1MAPTRAB9A
SCHEMBL31668207 0.84 TTR (0.50) TTRKMT2AMEN1MAPTRAB9A
SCHEMBL8057763 0.81 ESR1 (0.38) TTRKMT2AMEN1MAPTPOLB
SCHEMBL6053862 0.80 CYP3A4 (0.43) TTRKMT2AMEN1MAPTPOLB
SCHEMBL8060260 0.80 ESR1 (0.40) TTRKMT2AMEN1MAPTESR1
SCHEMBL8055949 0.80 SERPINE1 (0.41) TTRKMT2ALMNAKDM4EESR1
SCHEMBL1122760 0.79 HCAR2 (0.43) TTRKMT2AMEN1MAPTPOLB
SCHEMBL87887 0.79 HCAR2 (0.43) TTRKMT2AMEN1MAPTPOLB
SCHEMBL9319210 0.77 TTR (0.41) TTRKMT2AMEN1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570600-B2 Multifunctional linker compounds 20Bloc, Inc. (US) 2026-03-10 US disclosed
US-20250243148-A1 MULTIFUNCTIONAL LINKER COMPOUNDS 20Bloc, Inc. 2025-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243148-A1 MULTIFUNCTIONAL LINKER COMPOUNDS F13A1, MRPL21, SRRM2 TTR 2965/4885KMT2A 3699/4885MEN1 418/4885
US-12570600-B2 Multifunctional linker compounds CHN2, RCC2, COG1 TTR 1998/4885KMT2A 3226/4885MEN1 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.