Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | CYBB | P04839 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31668196 | 0.95 | TTR (0.51) | TTRNPC1RAB9AMAPTKMT2A | |
| SCHEMBL31668175 | 0.84 | TTR (0.48) | TTRNPC1RAB9AMAPTKMT2A | |
| SCHEMBL8532176 | 0.81 | ESR1 (0.42) | TTRNPC1RAB9AMAPTKMT2A | |
| SCHEMBL9304917 | 0.80 | AKR1C3 (0.44) | TTRNPC1RAB9AMAPTKMT2A | |
| SCHEMBL31668147 | 0.76 | CYBB (0.57) | NPC1RAB9AKMT2ACYBBPPARG | |
| SCHEMBL8057763 | 0.75 | ESR1 (0.38) | TTRMAPTKMT2AMEN1POLB | |
| SCHEMBL8060260 | 0.74 | ESR1 (0.40) | TTRMAPTKMT2AMEN1AKR1C4 | |
| SCHEMBL8055949 | 0.74 | SERPINE1 (0.41) | TTRKMT2AAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL17978154 | 0.73 | TDP1 (0.50) | NPC1RAB9AKMT2AMRGPRX4CA12 | |
| SCHEMBL6053862 | 0.72 | CYP3A4 (0.43) | TTRMAPTKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570600-B2 | Multifunctional linker compounds | 20Bloc, Inc. (US) | 2026-03-10 | — | — | US | disclosed |
| US-20250243148-A1 | MULTIFUNCTIONAL LINKER COMPOUNDS | 20Bloc, Inc. | 2025-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250243148-A1 | MULTIFUNCTIONAL LINKER COMPOUNDS | F13A1, MRPL21, SRRM2 | TTR 2965/4885NPC1 3479/4885RAB9A 707/4885 |
| US-12570600-B2 | Multifunctional linker compounds | CHN2, RCC2, COG1 | TTR 1998/4885NPC1 572/4885RAB9A 1840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.