Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPRF | P10586 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PLEC | Q15149 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055949 | 0.86 | SERPINE1 (0.41) | ESR1TTRPTPN1PTPN2PTPN11 | |
| SCHEMBL8060260 | 0.86 | ESR1 (0.40) | ESR1TTRPTPN1PTPN2PTPN11 | |
| SCHEMBL8532176 | 0.82 | ESR1 (0.42) | ESR1TTRPTPN1PTPN2PTPN11 | |
| SCHEMBL31668175 | 0.81 | TTR (0.48) | ESR1TTRPTPN1PTPN2PTPN11 | |
| SCHEMBL31668196 | 0.80 | TTR (0.51) | ESR1TTREGFRERBB2KMT2A | |
| SCHEMBL8057769 | 0.80 | AKR1C4 (0.42) | PTPN1EGFRERBB2MAOBMAOA | |
| SCHEMBL31668207 | 0.75 | TTR (0.50) | TTREGFRERBB2MEN1KMT2A | |
| SCHEMBL6053862 | 0.71 | CYP3A4 (0.43) | TTREGFRERBB2MEN1KMT2A | |
| SCHEMBL8055908 | 0.71 | CA12 (0.58) | ESR1PTPN1MAOBMAOAMEN1 | |
| SCHEMBL20472063 | 0.70 | KMT2A (0.59) | MAOBMAOAMEN1KMT2ASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785920-B1 | MULTIFUNCTIONAL CROSS-LINKING REAGENTS FOR HEMOGLOBIN, AND CROSS-LINKED HEMOGLOBIN CONJUGATES | KLUGER RONALD (CA) | 2000-05-17 | — | — | EP | claimed |
| EP-0785920-B1 | MULTIFUNCTIONAL CROSS-LINKING REAGENTS FOR HEMOGLOBIN, AND CROSS-LINKED HEMOGLOBIN CONJUGATES | KLUGER RONALD (CA) | 2000-05-17 | — | — | EP | disclosed |
| US-5811521-A | Multifunctional crosslinking reagents for hemoglobin, and crosslinked hemoglobin conjugates | KLUGER RONALD H (CA) | 1998-09-22 | — | — | US | disclosed |