SCHEMBL31668196

SCHEMBL31668196

O=C(OCc1cc(Br)cc(Br)c1O)c1cccc(C(=O)OCc2cc(Br)cc(Br)c2O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.51
CYBB P04839 1/20 0.46
RAB9A P51151 4/20 0.43
NPC1 O15118 3/20 0.43
MAPT P10636 3/20 0.42
PPARG P37231 1/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPK1 P28482 1/20 0.42
TSHR P16473 2/20 0.41
LMNA P02545 1/20 0.41
RXFP1 Q9HBX9 1/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
EGFR P00533 1/20 0.39
ERBB2 P04626 1/20 0.39
POLB P06746 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31668207 0.95 TTR (0.50) TTRCYBBRAB9ANPC1MAPT
SCHEMBL31668175 0.89 TTR (0.48) TTRCYBBRAB9ANPC1MAPT
SCHEMBL8532176 0.85 ESR1 (0.42) TTRCYBBRAB9ANPC1MAPT
SCHEMBL8057763 0.80 ESR1 (0.38) TTRMAPTALDH1A1EGFRERBB2
SCHEMBL9304917 0.79 AKR1C3 (0.44) TTRRAB9ANPC1MAPTTSHR
SCHEMBL8060260 0.79 ESR1 (0.40) TTRMAPTTSHRKMT2AESR1
SCHEMBL8055949 0.79 SERPINE1 (0.41) TTRKDM4ETSHRLMNAL3MBTL1
SCHEMBL6053862 0.76 CYP3A4 (0.43) TTRMAPTTSHRLMNAALDH1A1
SCHEMBL87887 0.75 HCAR2 (0.43) TTRMAPTTSHRLMNAALDH1A1
SCHEMBL1122760 0.75 HCAR2 (0.43) TTRMAPTTSHRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570600-B2 Multifunctional linker compounds 20Bloc, Inc. (US) 2026-03-10 US disclosed
US-20250243148-A1 MULTIFUNCTIONAL LINKER COMPOUNDS 20Bloc, Inc. 2025-07-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243148-A1 MULTIFUNCTIONAL LINKER COMPOUNDS F13A1, MRPL21, SRRM2 TTR 2965/4885CYBB 2958/4885RAB9A 707/4885
US-12570600-B2 Multifunctional linker compounds CHN2, RCC2, COG1 TTR 1998/4885CYBB 1854/4885RAB9A 1840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.