Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8063636 | 0.87 | HPGD (0.41) | HPGDSLC6A3CXCL8LMNAKMT2A | |
| SCHEMBL7746892 | 0.78 | SMN1; SMN2 (0.45) | HPGDCXCL8ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8061269 | 0.78 | HPGD (0.43) | HPGDSLC6A3LMNAKMT2AALDH1A1 | |
| SCHEMBL8057000 | 0.76 | HPGD (0.49) | HPGDCXCL8ALDH1A1KDM4ERAB9A | |
| SCHEMBL5054724 | 0.73 | SLC6A3 (0.47) | HPGDSLC6A3LMNAKMT2AALDH1A1 | |
| SCHEMBL7604366 | 0.70 | HPGD (0.40) | HPGDSLC6A3CXCL8LMNAKMT2A | |
| SCHEMBL18607331 | 0.70 | CXCL8 (0.58) | HPGDCXCL8ALDH1A1KDM4E | |
| SCHEMBL7609798 | 0.69 | CXCL8 (0.48) | HPGDCXCL8RAB9A | |
| SCHEMBL5059792 | 0.68 | HPGD (0.45) | HPGDSLC6A3LMNAKMT2AALDH1A1 | |
| SCHEMBL20472218 | 0.68 | CXCL8 (0.60) | CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6011021-A | GLUTAMATE-DERIVED HYDROXYPHOSPHINYL DERIVATIVE. | GUILFORD PHARMACEUTICALS INC. (US) | 2000-01-04 | — | — | US | disclosed |