Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8053961 | 0.80 | ADRA1D (0.47) | KDM4EPKMALDH1A1TDP1HTT | |
| Oxalic Acid SCHEMBL8057898 | 0.74 | ALDH1A1 (0.57) | KDM4EALDH1A1TDP1HTTMEN1 | |
| SCHEMBL5284933 | 0.72 | MMP1 (0.43) | KMT2ALMNA | |
| SCHEMBL27611534 | 0.70 | MTNR1A (0.58) | KDM4EPKMALDH1A1TDP1HTT | |
| SCHEMBL7416446 | 0.69 | GLA (0.47) | KDM4EALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL20556306 | 0.69 | ATM (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8053956 | 0.69 | HTR1A (0.58) | KDM4EALDH1A1MEN1KMT2AHTR1A | |
| Oxalic Acid SCHEMBL10681297 | 0.68 | MAPK1 (0.46) | KDM4EPKMALDH1A1TDP1HTT | |
| SCHEMBL6196730 | 0.68 | MTNR1A (0.77) | KDM4EPKMALDH1A1MEN1KMT2A | |
| SCHEMBL27736013 | 0.68 | HTR1A (0.53) | KDM4EPKMALDH1A1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051605-A | TREATING PSYCHOSIS AND SCHIZOPHRENIA USING A COMPOUND THAT IS AN ANTAGONIST OF DOPAMINE D4 RECEPTORS | WARNER-LAMBERT COMPANY (US) | 2000-04-18 | — | — | US | disclosed |