Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058437 | 0.77 | TBXAS1 (0.49) | FDPS | |
| SCHEMBL7608731 | 0.74 | CETP (0.42) | TSHRRAB9AGRM5CETPTAAR1 | |
| SCHEMBL8059146 | 0.72 | CETP (0.36) | GRM2GRM3POLBOPRM1OPRD1 | |
| SCHEMBL8061328 | 0.71 | L3MBTL1 (0.40) | GRM2GRM3TSHRPOLBOPRM1 | |
| SCHEMBL8046595 | 0.71 | OPRM1 (0.36) | GRM2GRM3POLBOPRM1OPRD1 | |
| SCHEMBL7744759 | 0.71 | SLC13A5 (0.46) | POLBCHRM3 | |
| SCHEMBL8059176 | 0.70 | OPRM1 (0.38) | GRM2GRM3POLBOPRM1OPRD1 | |
| SCHEMBL2318491 | 0.70 | TAAR1 (0.47) | TAAR1 | |
| SCHEMBL7746842 | 0.69 | OPRM1 (0.42) | GRM2GRM3OPRM1OPRD1OPRK1 | |
| SCHEMBL5053181 | 0.69 | TSHR (0.41) | TSHRRAB9APOLBOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046180-A | NAALADase inhibitors | GUILFORD PHARMACEUTICALS INC. (US) | 2000-04-04 | — | — | US | disclosed |