Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.49 |
| ▸ | FDPS | P14324 | 4/20 | 0.48 |
| ▸ | PTAFR | P25105 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059151 | 0.77 | GRM2 (0.38) | FDPS | |
| SCHEMBL8503461 | 0.76 | TBXAS1 (0.59) | TBXAS1FDPSCHRNA7TDP1L3MBTL1 | |
| SCHEMBL7641415 | 0.74 | TBXAS1 (0.54) | TBXAS1FDPSPTAFRCHRNA7EPHX2 | |
| SCHEMBL29475143 | 0.73 | LMNA (0.50) | FDPSCYP1A2CYP3A4TDP1BTN3A1 | |
| SCHEMBL8058433 | 0.72 | FDPS (0.53) | FDPSCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5497372 | 0.72 | KCNA5 (0.48) | TBXAS1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8065691 | 0.72 | CHRNA7 (0.53) | TBXAS1FDPSPTAFRCHRNA7TDP1 | |
| SCHEMBL4213129 | 0.72 | TBXAS1 (0.50) | TBXAS1FDPSPTAFRCYP1A2CYP3A4 | |
| SCHEMBL8046493 | 0.72 | FDPS (0.55) | FDPSCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8059117 | 0.71 | FDPS (0.58) | FDPSCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046180-A | NAALADase inhibitors | GUILFORD PHARMACEUTICALS INC. (US) | 2000-04-04 | — | — | US | disclosed |