SCHEMBL8061111

SCHEMBL8061111

CN(C)CCc1cc(N(C)C)cc(N(C)C)c1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.40
HTR2A P28223 6/20 0.37
HTR2C P28335 4/20 0.36
HTR1A P08908 4/20 0.36
HTR2B P41595 3/20 0.36
SLC6A4 P31645 2/20 0.36
TAAR1 Q96RJ0 3/20 0.34
DRD2 P14416 1/20 0.34
DRD1 P21728 1/20 0.33
HTR1D P28221 1/20 0.33
HTR1B P28222 1/20 0.33
HTR1E P28566 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
HTR7 P34969 1/20 0.33
DRD3 P35462 1/20 0.33
HTR5A P47898 1/20 0.33
HTR6 P50406 1/20 0.33
MEN1 O00255 1/20 0.32
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL487689 0.76 TSHR (0.41) MEN1KMT2A
SCHEMBL374864 0.71 MDM2 (0.45) MDM2HTR2AHTR2CHTR1AHTR2B
Acetic Acid SCHEMBL8809437 0.67 ALDH1A1 (0.41) MEN1KMT2A
SCHEMBL11278968 0.67 CYP2C19 (0.67) MDM2HTR2AHTR2CHTR1AHTR2B
SCHEMBL10557130 0.66 SHBG (0.47) MDM2HTR2AHTR2CHTR1AHTR2B
SCHEMBL8418972 0.65 MEN1 (0.54) MDM2HTR2AHTR2CHTR1AHTR2B
SCHEMBL11746409 0.64 MDM2 (0.40) MDM2HTR2AHTR2CHTR1AHTR2B
SCHEMBL6066009 0.64 SLC6A4 (0.44) MDM2HTR2AHTR2CHTR2BSLC6A4
SCHEMBL9418847 0.63 TYR (0.44) MEN1KMT2ATDP1
SCHEMBL10633892 0.63 SIGMAR1 (0.48) HTR2AHTR2CHTR2BSLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722428-B1 GLASS FIBRE SIZE COMPOSITION, METHOD USING SAME, AND RESULTING PRODUCTS VETROTEX FRANCE SA (FR) 2000-06-14 EP disclosed
US-5955195-A AT LEAST ONE REACTIVE EPOXY FUNCTION AND, OPTIONALLY, ONE OR MORE COMPONENTS HAVING AT LEAST ONE REACTIVE HYDROXY FUNCTION AND/OR ONE REACTIVE VINYL ETHER FUNCTION. VETROTEX FRANCE (FR) 1999-09-21 US disclosed
EP-0722428-A1 GLASS FIBRE SIZE COMPOSITION, METHOD USING SAME, AND RESULTING PRODUCTS VETROTEX FRANCE (FR) 1996-07-24 EP disclosed
WO-1996001233-A1 GLASS FIBRE SIZE COMPOSITION, METHOD USING SAME, AND RESULTING PRODUCTS VETROTEX FRANCE (FR) 1996-01-18 WO disclosed