Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28793603 | 0.82 | ALOX5 (0.53) | HSD17B10CYP3A4ALOX15ALDH1A1MEN1 | |
| SCHEMBL27947405 | 0.82 | ALOX5 (0.53) | HSD17B10CYP3A4ALOX15ALDH1A1MEN1 | |
| SCHEMBL12478792 | 0.82 | CYP3A4 (0.50) | HSD17B10CYP3A4ALDH1A1HPGDKDM4E | |
| SCHEMBL29875613 | 0.82 | ALOX15 (0.64) | HSD17B10CYP3A4ALOX15ALDH1A1HPGD | |
| SCHEMBL28871380 | 0.82 | HSD17B10 (0.70) | HSD17B10CYP3A4ALOX15ALDH1A1HPGD | |
| SCHEMBL25301803 | 0.82 | HSD17B10 (0.61) | HSD17B10CYP3A4ALOX15ALDH1A1HPGD | |
| SCHEMBL650894 | 0.82 | CYP3A4 (0.61) | HSD17B10CYP3A4ALOX15ALDH1A1HPGD | |
| SCHEMBL21582646 | 0.82 | HSD17B10 (0.61) | HSD17B10CYP3A4ALOX15ALDH1A1HPGD | |
| SCHEMBL116465 | 0.82 | CYP3A4 (0.61) | HSD17B10CYP3A4ALOX15ALDH1A1HPGD | |
| SCHEMBL29372308 | 0.82 | CYP3A4 (0.61) | HSD17B10CYP3A4ALOX15ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103436-A | A PHOTOCONDUCTIVE LAYER COMPRISING A HYDROXY FUNCTIONALIZED AROMATIC DIAMINE AND A HYDROXY FUNCTIONALIZED TRIARYLAMINE AND A CROSSLINKED POLYAMIDE MATRIX | XEROX CORPORATION (US) | 2000-08-15 | — | — | US | disclosed |